Barcelona snapped a four-match winless run in La Liga with a 4-2 home victory over title rivals Sevilla on Saturday to reclaim top spot but the triumph was marred by talisman Lionel Messi fracturing his arm and being ruled out for three weeks.
Sevilla sneaked into the last 32 of the Europa League on Wednesday with a 2-2 draw at home to Borussia Dortmund as the German side failed to translate their devastating domestic form into European success.
Barcelona retained the King's Cup with a 2-0 victory over Sevilla to complete a domestic double.
Sevilla coach Unai Emery has been picking the brains of Juande Ramos as he tries to plot the downfall of Ukrainian outsiders Dnipro Dnipropetrovsk in Wednesday's Europa League final.
Sevilla secured third place in the Primera Liga and automatic qualification for the Champions League when a last-minute header from Diego Perotti earned them a 1-0 home win over Deportivo Coruna on Saturday.
Argentine striker Lautaro Acosta scored an injury-time winner to give Sevilla a 2-1 victory at home to Athletic Bilbao in their King's Cup semi-final first leg on Wednesday.
Spain manager Luis de la Fuente left Barcelona's 17-year-old defender Pau Cubarsi and midfielders Marcos Llorente and Aleix Garcia out of his 26-man squad
The Copa del Rey semi-final draw will be made on Friday.
Manchester United, Sevilla and Celtic led a parade of clubs with continental pedigree to book the first places in this season's Europa League knockout stage.
Cristiano Ronaldo celebrated his recent Ballon d'Or award by scoring twice for the first time in a La Liga game this season as champions Real Madrid swept to a stunning 5-0 win over Sevilla on Saturday to go five points behind leaders Barcelona.
Sevilla, winners of the Europa League for the past two years, will play Shakhtar Donetsk in this season's semi-final.
Sevilla's love affair with the Europa League was immediately rekindled as last season's champions and three-time winners began this year's group stage with a 2-0 home victory over Feyenoord on Thursday.
Simeone's side leapfrogged Real Sociedad into fourth on 42 points, while Sevilla stayed third in the standings on 46 after beating Las Palmas 1-0, also on Sunday, thanks to a late strike from substitute Joaquin Correa
Twice UEFA Cup winners Sevilla failed to reach the knockout phase after a 1-0 defeat at Sampdoria eliminated the Spaniards. Sampdoria's victory sent them through from Group C along with VfB Stuttgart, who thumped Standard Liege 3-0 to progress to Friday's last 32 draw. Paris St Germain, twice winners Tottenham Hotspur, NEC Nijmegen and Olympiakos Piraeus also sealed places in the first knockout round.
Defender Gerard Pique grabbed a rare winner and Lionel Messi scored yet another beauty as Barcelona came from behind to beat Sevilla 2-1 at the Nou Camp on Sunday and reclaim an eight-point lead at the top of La Liga.
Sevilla and Valencia recorded opening day wins in La Liga, helping dispel some of the doubts surrounding their abilities to challenge for honours this season.
Luis Fabiano netted the equaliser and Frederic Kanoute struck twice to earn Sevilla a 3-1 comeback victory at home to a second-string Barcelona in the first leg of the Spanish Super Cup on Saturday.
The defending champions knocked out Osasuna while Espanyol triumphed over Werder Bremen.
Osasuna beat Bayer Leverkusen 1-0 at home in the UEFA Cup on Thursday to earn themselves an emphatic 4-0 win on aggregate and set up an all-Spanish tie against holders Sevilla in the semi-finals.
UEFA Cup holders Sevilla, rescued by a last-gasp goal in normal time from goalkeeper Andres Palop, kept their defence alive by overcoming Shakhtar Donetsk to reach the quarter-finals on Thursday.
Samir Nasri has left Manchester City for Sevilla on a season-long loan, the Premier League club announced on Wednesday. Like goalkeeper Joe Hart, who joined Torino on loan earlier, the former French international midfielder does not feature in new manager Pep Guardiola's plans.
Barcelona moved two points clear at the top of the table on Saturday after notching a 1-0 win at home to Real Sociedad while title challengers Sevilla beat Real Madrid 2-1.
Real Madrid warmed up for their crunch meeting against Barcelona by thrashing Sevilla 4-0 and coach Zinedine Zidane believes his team "can do great things" if they match the performance they produced against Unai Emery's side.
Sevilla striker Luis Fabiano scored twice in the second-half to give his side a 2-2 draw at home to struggling Malaga in La Liga on Saturday.
Sevilla's hopes of a place in European competition next season suffered a big blow when they let slip a one-goal lead to lose 5-1 at Getafe in La Liga on Monday.
Alvaro Morata again proved decisive from the bench by striking a late winner against Athletic Bilbao and firing a lacklustre Real Madrid to the top of La Liga on Sunday. The Spain international has been afforded limited opportunities in his first season back at Real following two years with Juventus, struggling to usurp first choice forwards Gareth Bale, Cristiano Ronaldo and Karim Benzema. Morata has made just four league starts, but has scored four times in all competitions.
Atletico Madrid's Jackson Martinez scored his first goal for the club when he came off the bench and curled in a superb effort to seal a hard-fought 3-0 victory at Sevilla in La Liga on Sunday.
Champions League winners AC Milan clinched an emotional European Super Cup for a record fifth time with a 3-1 victory over Sevilla on Friday.
Olympique de Marseille were the fall guys on a hectic opening night of Europa League group stage action as German club Eintracht Frankfurt returned from the south of France with a surprise 2-1 victory on Thursday.
Liverpool romed into the Europa League final with a 3-0 win over Villarreal on another magical night at Anfield to tee up a showpiece clash with holders Sevilla who swatted away visitors Shakhtar Donetsk 3-1 on Thursday.
Xavi mentioned again on Saturday that the club faced problems. Similar comments had reportedly annoyed Laporta earlier in the season.
Dani Alves faces charges of sexual assault of a woman in a Barcelona nightclub last December.
Emotions ran high as Nantes paid tribute to their former player Emiliano Sala on Wednesday in their first game since the Argentine went missing in a light aircraft over the English Channel.
A Ronaldinho double and solo goal from Lionel Messi gave Barcelona a 3-1 home win against high-flying Sevilla.
Ivan Toney, once Brentford's lynchpin in attack, has moved to Al-Ahli for 40 million pounds ($52.50 million).
Cristiano Ronaldo scored his 400th goal for Real Madrid as Zinedine Zidane's side closed in on a first La Liga title since 2012, easing to a 4-1 win over Sevilla on Sunday while Neymar hit a hat-trick for Barcelona, who thrashed Las Palmas 4-1.
Images from Champions League matches played across Europe on Tuesday
Real Madrid's stuttering start to La Liga continued when they lost 1-0 at Sevilla to slip eight points behind leaders Barcelona who were 4-1 victors at Getafe earlier on Saturday.
Sevilla won the second leg final of the Spanish Super Cup 5-3.
A 5-1 victory enabled them retain the top spot in the Primera Liga.